Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains
نویسندگان
چکیده
منابع مشابه
Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains.
Mutations causing expansions of polyalanine domains are responsible for nine hereditary diseases. Other GC-rich sequences coding for some polyalanine domains were found to be polymorphic in human. These observations prompted us to identify all sequences in the human genome coding for polyalanine stretches longer than four alanines and establish their degree of polymorphism. We identified 494 an...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2003
ISSN: 1460-2083,0964-6906
DOI: 10.1093/hmg/ddg329